• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

产前酒精摄入与大鼠旷场行为:测试时年龄的影响

Prenatal alcohol consumption and open-field behaviour in rats: effects of age at time of testing.

作者信息

Bond N W, Di Giusto E L

出版信息

Psychopharmacology (Berl). 1977 May 9;52(3):311-2. doi: 10.1007/BF00426717.

DOI:10.1007/BF00426717
PMID:406636
Abstract

Throughout gestation pregnant Wistar rats consumed a nutritious liquid diet containing 35% ethanol-derived calories. Control mothers were fed lab-chow. Subsequently, the offspring of the ethanol-fed mothers displayed significantly greater activity (ambulation) in an open-field test at 28 and at 56 days of age, but not at 112 days of age. No differences in defecation were observed at any age.

摘要

在整个妊娠期,怀孕的Wistar大鼠食用一种富含营养的流质饮食,其中35%的热量来自乙醇。对照母鼠喂食实验室标准饲料。随后,食用乙醇的母鼠所产的后代在28日龄和56日龄的旷场试验中表现出明显更高的活动量(行走),但在112日龄时没有差异。在任何年龄都未观察到排便方面的差异。

相似文献

1
Prenatal alcohol consumption and open-field behaviour in rats: effects of age at time of testing.产前酒精摄入与大鼠旷场行为:测试时年龄的影响
Psychopharmacology (Berl). 1977 May 9;52(3):311-2. doi: 10.1007/BF00426717.
2
Effects of prenatal alcohol consumption on open-field behaviour and alcohol preference in rats.
Psychopharmacologia. 1976 Mar 16;46(2):163-5. doi: 10.1007/BF00421386.
3
Maternal dietary ethanol consumption is associated with hypertriglyceridemia in adult rat offspring.孕期母体摄入乙醇与成年子代大鼠的高甘油三酯血症有关。
Alcohol Clin Exp Res. 2002 Jun;26(6):848-55.
4
Avoidance conditioning and Hebb-Williams maze performance in rats treated prenatally with alcohol.
Psychopharmacology (Berl). 1978 Jun 15;58(1):69-71. doi: 10.1007/BF00426792.
5
Prenatal exposure to ethanol: association between increased gestational length and offspring mortality.产前乙醇暴露:妊娠期延长与后代死亡率之间的关联。
Neurobehav Toxicol Teratol. 1982 Sep-Oct;4(5):501-3.
6
Prenatal ethanol exposure fails to affect stimulus reactivity in the rat.产前乙醇暴露不会影响大鼠的刺激反应性。
Alcohol. 1986 Jan-Feb;3(1):1-4. doi: 10.1016/0741-8329(86)90062-5.
7
Ethanol ingestion during pregnancy: effects on pregnant rats and their offspring.
J Nutr. 1982 Jan;112(1):98-103. doi: 10.1093/jn/112.1.98.
8
Effects of pregnancy and progesterone on the consumption of ethanol by the high ethanol preferring (HEP) rat.
Alcohol Alcohol. 2000 Jul-Aug;35(4):344-50. doi: 10.1093/alcalc/35.4.344.
9
Prenatal ethanol and stress in mice: 1. Pup behavioral development and maternal physiology.小鼠孕期乙醇暴露与应激:1. 幼崽行为发育与母体生理学
Physiol Behav. 1989 Mar;45(3):533-40. doi: 10.1016/0031-9384(89)90070-x.
10
Effects of alcohol consumption during pregnancy on subsequent maternal behaviour in rats.孕期饮酒对大鼠产后母性行为的影响。
Pharmacol Biochem Behav. 1982 Jul;17(1):125-9. doi: 10.1016/0091-3057(82)90273-8.

引用本文的文献

1
Vinpocetine, a Phosphodiesterase Type 1 Inhibitor, Mitigates Locomotor Hyperactivity in Female Mice Exposed to Lead During Development.长春西汀,一种1型磷酸二酯酶抑制剂,可减轻发育期间暴露于铅的雌性小鼠的运动性多动。
Brain Sci. 2025 Feb 2;15(2):150. doi: 10.3390/brainsci15020150.
2
Evidence for long-lasting alterations in the fecal microbiota following prenatal alcohol exposure.有证据表明,产前酒精暴露会导致粪便微生物群发生持久改变。
Alcohol Clin Exp Res. 2022 Apr;46(4):542-555. doi: 10.1111/acer.14784. Epub 2022 Feb 17.
3
Individual subject meta-analysis of parameters for Giardia duodenalis shedding in animal experimental models.

本文引用的文献

1
The role of catecholamines in behavioral arousal during ontogenesis.儿茶酚胺在个体发育过程中行为唤醒中的作用。
Psychopharmacologia. 1973 Jul 19;31(3):253-64. doi: 10.1007/BF00422515.
2
The influence of ethanol administered to pregnant rats on tyrosine hydroxylase activity of their offspring.
Psychopharmacologia. 1973;32(2):151-6. doi: 10.1007/BF00428685.
3
Behavioral teratogenesis: a critical evaluation.
Pharmacol Biochem Behav. 1976 Feb;4(2):191-200. doi: 10.1016/0091-3057(76)90014-9.
4
动物实验模型中十二指肠贾第鞭毛虫脱落参数的个体受试者荟萃分析。
Biomed Res Int. 2014;2014:476142. doi: 10.1155/2014/476142. Epub 2014 Apr 1.
4
Determination of motor activity and anxiety-related behaviour in rodents: methodological aspects and role of nitric oxide.啮齿动物运动活动及焦虑相关行为的测定:方法学要点及一氧化氮的作用
Interdiscip Toxicol. 2013 Sep;6(3):126-35. doi: 10.2478/intox-2013-0020.
5
In utero alcohol exposure, epigenetic changes, and their consequences.子宫内酒精暴露、表观遗传变化及其后果。
Alcohol Res. 2013;35(1):37-46.
6
Individual subject meta-analysis of parameters for Cryptosporidium parvum shedding and diarrhoea in animal experimental models.个体受试的隐孢子虫参数的荟萃分析,这些参数与动物实验模型中的隐孢子虫脱落和腹泻有关。
Epidemiol Infect. 2013 Aug;141(8):1662-78. doi: 10.1017/S0950268812002294. Epub 2012 Oct 16.
7
Altered spatial learning and delay discounting in a rat model of human third trimester binge ethanol exposure.人类妊娠晚期暴饮乙醇大鼠模型中的空间学习和延迟折扣改变。
Behav Pharmacol. 2012 Feb;23(1):54-65. doi: 10.1097/FBP.0b013e32834eb07d.
8
The use of docosahexaenoic acid supplementation to ameliorate the hyperactivity of rat pups induced by in utero ethanol exposure.二十二碳六烯酸补充剂用于改善宫内乙醇暴露诱导的幼鼠多动。
Environ Health Prev Med. 2000 Oct;5(3):103-10. doi: 10.1265/ehpm.2000.103.
9
Tolerance, opioid-induced allodynia and withdrawal associated allodynia in infant and young rats.幼鼠的阿片类药物诱导的耐受性、痛觉过敏和戒断相关痛觉过敏
Neuroscience. 2007 Jan 5;144(1):247-62. doi: 10.1016/j.neuroscience.2006.08.078. Epub 2006 Oct 19.
10
Paternal alcohol exposure: paradoxical effect in mice and rats.
Psychopharmacology (Berl). 1990;100(2):159-64. doi: 10.1007/BF02244399.
Effects of prenatal alcohol consumption on open-field behaviour and alcohol preference in rats.
Psychopharmacologia. 1976 Mar 16;46(2):163-5. doi: 10.1007/BF00421386.