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产前酒精摄入与大鼠旷场行为:测试时年龄的影响

Prenatal alcohol consumption and open-field behaviour in rats: effects of age at time of testing.

作者信息

Bond N W, Di Giusto E L

出版信息

Psychopharmacology (Berl). 1977 May 9;52(3):311-2. doi: 10.1007/BF00426717.

Abstract

Throughout gestation pregnant Wistar rats consumed a nutritious liquid diet containing 35% ethanol-derived calories. Control mothers were fed lab-chow. Subsequently, the offspring of the ethanol-fed mothers displayed significantly greater activity (ambulation) in an open-field test at 28 and at 56 days of age, but not at 112 days of age. No differences in defecation were observed at any age.

摘要

在整个妊娠期,怀孕的Wistar大鼠食用一种富含营养的流质饮食,其中35%的热量来自乙醇。对照母鼠喂食实验室标准饲料。随后,食用乙醇的母鼠所产的后代在28日龄和56日龄的旷场试验中表现出明显更高的活动量(行走),但在112日龄时没有差异。在任何年龄都未观察到排便方面的差异。

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