den Hartog G, Mulder C J, Thies J E, Wiersma T G
Dept of Hepatogastroenterology, Rijnstate Hospital Arnhem, The Netherlands.
Scand J Gastroenterol Suppl. 1998;225:41-6. doi: 10.1080/003655298750027218.
The number of dyspeptic patients with upper abdominal pain that are referred for investigation is increasing and will undoubtedly continue to increase, because these days peptic ulcer disease is increasingly becoming a primary care management issue, the specialist being left to deal with the patients who cannot be helped by antibiotics and antisecretory drugs prescribed by their general practitioner. Many of these patients are referred for an upper endoscopy to rule out organic disease. Carefully taken history, however, shows that a great number of those dyspeptics, on the basis of their clinical manifestations, do have a functional gastrointestinal disorder, representing the 'irritable gut'. A probable better term reflecting the direct relation is the syndrome of 'the constipated stomach'. In our opinion these patients are an important and increasing clinical problem for general practitioners, gastroenterologists, surgeons and physicians. The aim of this article is to make the practitioner aware of advancements in understanding pathophysiologic and psychosocial processes, as well as to give an overview of the great overlap between many functional gastrointestinal disorders, the important role of history-taking and some insights into the functional rectal outlet syndrome.
因上腹部疼痛而被转诊接受检查的消化不良患者数量正在增加,而且无疑还会继续增加,因为如今消化性溃疡病越来越成为基层医疗管理的问题,专科医生只能处理那些全科医生开的抗生素和抗分泌药物无法治疗的患者。许多此类患者会被转诊接受上消化道内镜检查以排除器质性疾病。然而,仔细询问病史会发现,大量此类消化不良患者根据其临床表现确实患有功能性胃肠病,也就是“易激肠”。一个可能更能反映直接关系的更好术语是“便秘胃”综合征。我们认为,这些患者对于全科医生、胃肠病学家、外科医生和内科医生来说是一个日益重要的临床问题。本文旨在让从业者了解在理解病理生理和心理社会过程方面的进展,概述许多功能性胃肠病之间的巨大重叠、病史采集的重要作用以及对功能性直肠出口综合征的一些见解。