Malhotra S, Varma V K, Misra A K, Das S, Wig N N, Santosh P J
Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Acta Psychiatr Scand. 1998 Feb;97(2):125-31. doi: 10.1111/j.1600-0447.1998.tb09974.x.
This is a comparative study of patients with acute-onset, non-affective, non-organic, remitting psychoses and with non-remitting or schizophrenic psychoses in India. Two groups of patients with acute remitting and non-remitting or schizophrenic psychoses were compared with regard to the following variables: month of onset of psychosis; presence of stress, particularly fever, within 4 weeks preceding the onset of psychosis; childbirth within 12 weeks preceding the onset of psychosis; gender differences. It was found that the acute remitting psychoses showed an overrepresentation of females, a higher frequency of associated stress preceding the onset of psychosis, more often had onset during the summer months, i.e. between May and September, and had fever and childbirth preceding the onset of psychosis in a significantly higher proportion of patients, compared to acute non-remitting psychoses or schizophrenia. The implications of the findings which point towards biological factors in the aetiology of acute remitting psychoses are discussed.
这是一项针对印度急性起病、非情感性、非器质性、缓解性精神病患者以及非缓解性或精神分裂症性精神病患者的对比研究。将两组急性缓解性和非缓解性或精神分裂症性精神病患者在以下变量方面进行了比较：精神病发作月份；精神病发作前4周内是否存在应激，尤其是发热；精神病发作前12周内是否分娩；性别差异。结果发现，与急性非缓解性精神病或精神分裂症相比，急性缓解性精神病患者中女性比例过高，精神病发作前相关应激的频率更高，发病更多集中在夏季月份，即5月至9月之间，且发病前有发热和分娩情况的患者比例显著更高。文中讨论了这些指向急性缓解性精神病病因中生物学因素的研究结果的意义。
