Heymann S J, Sell R, Brewer T F
Department of Health and Social Behavior, Harvard School of Public Health, Boston, MA 02115, USA.
Am J Public Health. 1998 Mar;88(3):442-5. doi: 10.2105/ajph.88.3.442.
This study examined how patient acceptability influences the effectiveness of directly observed therapy for tuberculosis.
Decision and sensitivity analyses were used in assessing influences.
If mandatory directly observed therapy discourages 6% of initial tuberculosis patients (range: 4% to 10%) from seeking care, then such therapy will be less effective than self-administered therapy. Directly observed therapy is more effective than repeated self-administered therapy for patients failing to complete initial treatment unless 32% (range: 27% to 38%) of patients avoid seeking care.
Patient acceptability must be taken into consideration before selecting public health strategies.
本研究探讨了患者的接受程度如何影响结核病直接督导治疗的效果。
采用决策分析和敏感性分析来评估影响因素。
如果强制直接督导治疗导致6%（范围：4%至10%）的初治结核病患者不愿寻求治疗，那么这种治疗的效果将不如自我给药治疗。对于未能完成初始治疗的患者，直接督导治疗比重复自我给药治疗更有效，除非32%（范围：27%至38%）的患者不愿寻求治疗。
在选择公共卫生策略之前，必须考虑患者的接受程度。
