Kasabov R, Nachev S
Vet Med Nauki. 1976;13(2):19-26.
An enzootic of necrotic dermatosis in hen layers was described. The changes consisted in that they had constant localization and demarkated sites on the skin between the back and the neck. The disease was observed on a farm for 5000 layers in the course of two consecutive years. All birds contracted the disease and in the first year they recovered the 10 months; in second year they recovered for three months. Each bird showed symptoms for 3 weeks. The skin lesions resulted in cicatrization. The etiologic agent (a Pasteurella-like organism) was isolated from the necrotic foci. It proved pathogenic for albino mice and manifested biochemical activity and morphology characteristic of Pasteurella multocida. The disease was successfully reproduced with a broth culture applied on a scarified skin of test birds. Histopathologically, the spontaneous lesions proved undistinguishable from the experimental ones and represented coagulation necrosis of the epidermis, derm, and subcutis. It is supposed that the constant localization was due to the porte d'entrer of the infection, associated with the bad habit of picage on the neck as demonstrated on a large scale by the birds of the infected flock. This is characteristic of some lines of the White Leghorn breed.
描述了一起蛋鸡坏死性皮炎的地方性流行。病变特点是在鸡的背部和颈部之间的皮肤有固定的发病部位和界限分明的病灶。在一个饲养5000只蛋鸡的农场连续两年观察到这种疾病。所有鸡只都感染了该病，第一年10个月后康复；第二年3个月后康复。每只鸡的症状持续3周。皮肤病变导致瘢痕形成。从坏死病灶中分离出病原体（一种类似巴氏杆菌的微生物）。它对白化小鼠具有致病性，并表现出多杀性巴氏杆菌的生化活性和形态特征。用肉汤培养物接种于试验鸡划破的皮肤上，成功地复制出了该病。组织病理学检查显示，自然病变与实验病变无法区分，均表现为表皮、真皮和皮下组织的凝固性坏死。据推测，固定的发病部位是由于感染的入口所致，这与感染鸡群的鸡大量存在的颈部啄癖不良习惯有关。这是白来航鸡某些品系的特征。
