Department of Otolaryngology, Asan Medical Center, Ulsan University School of Medicine, Seoul, Korea.
Clin Exp Otorhinolaryngol. 2009 Sep;2(3):151-4. doi: 10.3342/ceo.2009.2.3.151. Epub 2009 Sep 23.
A petrous apex cholesterol granuloma (PACG) is the most common lesion of the petrous apex mass. Affected patients present with various symptoms such as hearing loss, vertigo, headache, tinnitus, facial spasms, and diplopia. We report the case of a 32-yr-old man with a PACG, who was first misdiagnosed with Ménière's disease. He was placed on a low-salt diet, and prescribed medication from another hospital, for several months, but the symptoms persisted and worsened. The patient presented to the emergency room complaining of left facial twitching and numbness. To rule out a central neurological lesion, temporal bone magnetic resonance imaging was carried out and a 2.5 cm mass with high signal intensity on T1- and T2-weighted imaging, without gadolinium enhancement, was found. Because of the hearing and facial problems, we drained cholesterol-bearing material via an infralabyrinthine approach using a computer aided image-guided surgical device, the BrainLAB(R). After the operation, the vertigo and hearing loss were no longer present. It is likely that the patent's Ménière's disease-like symptoms were due to the compression of the endolymphatic sac by a PACG.
岩尖胆固醇肉芽肿(PACG)是岩尖肿块中最常见的病变。受影响的患者表现出各种症状,如听力损失、眩晕、头痛、耳鸣、面部痉挛和复视。我们报告了一例 32 岁男性 PACG 患者,他最初被误诊为梅尼埃病。他接受了低盐饮食,并在另一家医院开了几个月的药物治疗,但症状持续且恶化。患者因左侧面部抽搐和麻木到急诊室就诊。为排除中枢神经系统病变,进行了颞骨磁共振成像,发现 2.5 厘米大小的肿块,T1 和 T2 加权成像呈高信号,无钆增强。由于听力和面部问题,我们使用计算机辅助图像引导手术设备 BrainLAB(R)经迷路下途径引流含胆固醇的物质。手术后,眩晕和听力损失不再存在。患者类似梅尼埃病的症状可能是由于 PACG 压迫内淋巴管囊所致。