Levy S, Compagnoni L, Myers E W, Stormo G D
University of Colorado, Boulder 80309-0347, USA.
Bioinformatics. 1998;14(1):74-80. doi: 10.1093/bioinformatics/14.1.74.
To provide a graphical interface for the generation, display and manipulation of a sequence landscape that will run on all X-windows-based Unix workstations.
The sequence landscape approach enables the representation of the frequency of occurrence of all query sequence sub-words within a database. The landscape approach can detect tandem and other repeating word motifs, specific sub-words that are over-represented words in a particular database using Markov probability and the preference for sub-words belonging to either one of two databases. All these features aid in the classification of a query sequence. Given the open-text format for sequences and databases, the Xlandscape tool can be applied to a wide range of problems.
提供一个图形界面,用于生成、显示和操作序列景观,该界面将在所有基于X窗口的Unix工作站上运行。
序列景观方法能够表示数据库中所有查询序列子词的出现频率。景观方法可以检测串联和其他重复词基序、特定子词,这些子词在特定数据库中使用马尔可夫概率过度表示,以及对属于两个数据库之一的子词的偏好。所有这些特征有助于对查询序列进行分类。鉴于序列和数据库的开放文本格式,Xlandscape工具可应用于广泛的问题。