Leukoedema: an epidemiological study in white and African Americans.

Leukoedema, a benign grayish-white lesion which characteristically involves the oral mucosa of humans, was once indicated as a probable precursor to leukoplakia. The author reports an incidence of fifty-three percent in a population of 13,000 white and African Americans who reside in the Southeastern region of the United States. This longitudinal study revealed that the incidence of leukoedema per 1,000 persons increased with age in both ethnic groups up to ages 40-49 and then declined systematically. There was no sex predilection. The occurrence of leukoedema was significantly greater in African Americans.