Against all odds: positive life experiences of people with advanced amyotrophic lateral sclerosis.

The study discussed in this article describes the nature of positive life experiences of 13 people coping exceptionally well while living with advanced amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, and the resulting significant physical disability. The most powerful themes to emerge were the use of cognitive reappraisal, reframing, and intellectual stimulation as coping mechanisms; the development of wisdom; and the vital importance of interpersonal relationships. On the basis of our findings, we make suggestions for ways professionals can assist people with ALS and their significant others.