Mariani G L, Carlo W A
Division of Neonatology, University of Alabama at Birmingham, USA.
Clin Perinatol. 1998 Mar;25(1):33-48.
Conventional mechanical ventilation continues to be the standard mode of support for neonates with respiratory failure. Controversies regarding the selection of optimal ventilatory strategies still abound. A deep understanding of physiologic concepts as well as a critical appraisal of the literature is needed to optimize the ventilatory management of the newborn. Principles of gas exchange, pulmonary mechanics and control of breathing are reviewed in the context of their relevance during mechanical ventilation. The application of these concepts to the ventilatory strategies for the management of infants with respiratory distress is presented, and current controversies are emphasized.
传统机械通气仍然是呼吸衰竭新生儿的标准支持模式。关于最佳通气策略选择的争议仍然很多。需要深入理解生理概念并对文献进行批判性评估，以优化新生儿的通气管理。在机械通气过程中，结合气体交换、肺力学和呼吸控制的相关性对其原理进行综述。介绍了这些概念在呼吸窘迫婴儿通气策略中的应用，并强调了当前的争议。
