Fontela Paula Caitano, Prestes Renata Bernardy, Forgiarini Luiz Alberto, Friedman Gilberto
Programa de Pós-Graduação em Ciências Pneumológicas, Universidade Federal do Rio Grande do Sul - Porto Alegre (RS), Brasil.
Curso de Mestrado Acadêmico em Biociências e Reabilitação, Centro Universitário Metodista IPA - Porto Alegre (RS), Brasil.
Rev Bras Ter Intensiva. 2017 Jan-Mar;29(1):77-86. doi: 10.5935/0103-507X.20170012.
: To review the literature on the use of variable mechanical ventilation and the main outcomes of this technique.
: Search, selection, and analysis of all original articles on variable ventilation, without restriction on the period of publication and language, available in the electronic databases LILACS, MEDLINE®, and PubMed, by searching the terms "variable ventilation" OR "noisy ventilation" OR "biologically variable ventilation".
: A total of 36 studies were selected. Of these, 24 were original studies, including 21 experimental studies and three clinical studies.
: Several experimental studies reported the beneficial effects of distinct variable ventilation strategies on lung function using different models of lung injury and healthy lungs. Variable ventilation seems to be a viable strategy for improving gas exchange and respiratory mechanics and preventing lung injury associated with mechanical ventilation. However, further clinical studies are necessary to assess the potential of variable ventilation strategies for the clinical improvement of patients undergoing mechanical ventilation.
回顾关于使用可变机械通气及其主要结果的文献。
通过在电子数据库LILACS、MEDLINE®和PubMed中搜索“可变通气”或“噪音通气”或“生物可变通气”等术语，对所有关于可变通气的原始文章进行检索、筛选和分析，不受发表时间和语言限制。
共筛选出36项研究。其中，24项为原创性研究，包括21项实验研究和3项临床研究。
多项实验研究报告了不同的可变通气策略在使用不同的肺损伤模型和健康肺模型时对肺功能的有益影响。可变通气似乎是改善气体交换和呼吸力学以及预防与机械通气相关的肺损伤的可行策略。然而，需要进一步的临床研究来评估可变通气策略对接受机械通气患者临床改善的潜力。
