结节病：家庭接触研究。
Sarcoidosis: family contact study.
作者信息
Fité E, Alsina J M, Antó J M, Morera J
机构信息
Pneumology Department, Germans Trias i, Pujol University Hospital, Badalona, Spain.
出版信息
Respiration. 1998;65(1):34-9. doi: 10.1159/000029225.
AIM
To assess the familial aggregation in sarcoidosis in our environment.
METHODS
The medical centers of Catalonia (Spain) were approached to identify, retrospectively, patients diagnosed as sarcoidosis from 1986 to 1988. 245 sarcoidosis cases were recorded (annual incidence: 1.36/100,000 inhabitants). Finally, in 1990 a telephone questionnaire was administered to 188 sarcoidosis cases.
RESULTS
These cases reported 3,757 familial contacts, 5 of whom had confirmed sarcoidosis. The clinical presentation of familial sarcoidosis was similar to nonfamilial sarcoidosis, only Löfgren syndrome stood out. The prevalence of sarcoidosis among familial contacts was 1.33/1,000.
CONCLUSIONS
The familial association is low and corresponds with the low annual incidence in our community.
目的
评估我们环境中结节病的家族聚集性。
方法
联系了加泰罗尼亚（西班牙）的医疗中心，以回顾性地识别1986年至1988年期间被诊断为结节病的患者。记录了245例结节病病例（年发病率：1.36/10万居民）。最后，在1990年对188例结节病病例进行了电话问卷调查。
结果
这些病例报告了3757名家族成员，其中5人确诊患有结节病。家族性结节病的临床表现与非家族性结节病相似，只有 Löfgren 综合征较为突出。家族成员中结节病的患病率为1.33/1000。
结论
家族关联性较低，与我们社区的低年发病率相符。
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