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加泰罗尼亚结节病的流行病学:1979 - 1989年

Epidemiology of sarcoidosis in Catalonia: 1979-1989.

作者信息

Fité E, Alsina J M, Mañá J, Pujol R, Ruiz J, Morera J

机构信息

Respiratory Department, University Hospital Germans Trias i Pujol, Badalona, Spain.

出版信息

Sarcoidosis Vasc Diffuse Lung Dis. 1996 Sep;13(2):153-8.

PMID:8893385
Abstract

For the purpose of estimating the incidence rate and clinico-epidemiological characteristics of sarcoidosis in Catalonia (a country comprising the provinces of Barcelona, Tarragona, Lleida and Girona, with a total population of 6 million people), we did a retrospective study of new cases diagnosed in the country's qualified hospitals during 1979 and the three-year period from 1986 to 1988. The annual incidence rate in the province of Barcelona was 1.2/100,000 in 1979 and 1.5/100,000 in 1988. 245 cases were diagnosed in Catalonia in the three-year period covering 1986-88, the annual incidence rate being 1.36/100,000 inhabitants. We describe here the characteristics of this series of 245 cases (which is the first one representative of the whole of Catalonia), and compare them with those of other series published previously. We conclude that the incidence of sarcoidosis in our country is one of the lowest in Europe, with no significant variations observed over ten years. The most relevant clinico-epidemiological characteristics are its clear predominance in women (3:1), and the high frequency of Löfgren's syndrome (48% of cases), whose incidence is significantly higher in springtime.

摘要

为了估算加泰罗尼亚(一个由巴塞罗那、塔拉戈纳、莱里达和赫罗纳省组成,总人口达600万的地区)结节病的发病率及临床流行病学特征,我们对1979年以及1986年至1988年这三年期间在该地区合格医院诊断出的新病例进行了回顾性研究。1979年巴塞罗那省的年发病率为1.2/10万,1988年为1.5/10万。在1986 - 1988年这三年期间,加泰罗尼亚共诊断出245例病例,年发病率为1.36/10万居民。我们在此描述这245例病例(这是首个代表整个加泰罗尼亚地区的病例系列)的特征,并将其与先前发表的其他病例系列进行比较。我们得出结论,我国结节病的发病率是欧洲最低的之一,十年间未观察到显著变化。最相关的临床流行病学特征是其在女性中明显占优势(3:1),以及Löfgren综合征的高发病率(48%的病例),其发病率在春季显著更高。

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