Jenkinson C, Stradling J, Petersen S
Department of Public Health, University of Oxford, Institute of Health Sciences, UK.
Qual Life Res. 1998 Feb;7(2):95-100. doi: 10.1023/a:1008845123907.
The purpose of this paper is to compare three approaches to the measurement of patient-reported health status which produce summary scales of health status: the Patient-generated Index (PGI) is a measure of individual quality of life (QoL), the EuroQol is a measure of QoL the results of which are weighted by utility values gained from community surveys and the SF-36 which produces two summary scales of health status (the physical component summary (PCS) and the mental component summary (MCS) scores). A follow-up interview survey of patients with obstructive sleep apnoea (OSA) was conducted. The patients received continuous positive airways pressure therapy (CPAP) between the two administrations of the questionnaires. One hundred patients presenting with OSA and who were suitable for CPAP therapy were asked if they would take part in the study. The results on the PGI, EuroQol EQ-5D utility weighted scores and 'thermometer' scores and SF-36 physical and mental summary scores were measured. Eighty-nine respondents provided sufficient data to calculate PGI and EuroQol scores and 86 patients provided sufficient data to calculate SF-36 summary scores. The PGI indicated substantial improvement after CPAP treatment whereas the EuroQol indicated little or no improvement on either utility weighted or thermometer scores. The SF-36 PCS and MCS scores were lower than those of the general population at baseline, but had improved to the normative levels after treatment. The EuroQol provided a substantially different picture of change to either of the ones gained from the SF-36 or PGI. It is suggested that the EuroQol does not contain questions which relate to important aspects of health and well-being and may not accurately reflect the health state of individuals. Consequently, caution must be exercised to assure that an appropriate instrument has been employed when using health outcomes data to assess or prioritize available health care treatments.
患者生成指数（PGI）是一种个体生活质量（QoL）的测量方法，欧洲生活质量量表（EuroQol）是一种生活质量测量方法，其结果通过从社区调查中获得的效用值进行加权，而SF-36则生成两个健康状况汇总量表（身体成分汇总量表（PCS）和心理成分汇总量表（MCS）得分）。对阻塞性睡眠呼吸暂停（OSA）患者进行了随访访谈调查。患者在两次问卷调查之间接受持续气道正压通气治疗（CPAP）。询问了100名患有OSA且适合CPAP治疗的患者是否愿意参加该研究。测量了PGI、欧洲生活质量量表EQ-5D效用加权得分和“温度计”得分以及SF-36身体和心理汇总得分的结果。89名受访者提供了足够的数据来计算PGI和欧洲生活质量量表得分，86名患者提供了足够的数据来计算SF-36汇总得分。PGI表明CPAP治疗后有显著改善，而欧洲生活质量量表表明效用加权得分或温度计得分几乎没有改善。SF-36的PCS和MCS得分在基线时低于一般人群，但治疗后已改善至正常水平。欧洲生活质量量表所呈现的变化情况与从SF-36或PGI中获得的变化情况有很大不同。有人认为，欧洲生活质量量表不包含与健康和幸福的重要方面相关的问题，可能无法准确反映个体的健康状况。因此，在使用健康结果数据评估或确定现有医疗保健治疗的优先级时，必须谨慎确保使用了合适的工具。
