Mrsny R J
Department of Pharmaceutical Research and Development, Genentech, Inc., San Francisco, California 94080, USA.
J Drug Target. 1997;5(1):5-9. doi: 10.3109/10611869708995852.
Progress in the development of drug targeting technologies is advancing at an ever-increasing rate as we hurtle toward the new millennium. Examination of just the past three years of the drug delivery technology patient literature suggests that what was previously thought impossible may now be a reality. As one goes through this literature, the breadth and ingenuity of many of these approaches are obvious. As in the inaugural article, I have grouped information gathered from this search into areas of mucosal targeting, organ and/or tissue targeting, tumor targeting and focal delivery. The patent applications described in this article represent a sampling of the work in these areas, with particular attention being paid to a few of the more novel or intriguing claims.
随着我们飞速迈向新千年，药物靶向技术的发展正以前所未有的速度推进。仅审视过去三年有关药物递送技术的患者文献就会发现，以前认为不可能的事情如今或许已成为现实。翻阅这些文献时，许多此类方法的广度和独创性显而易见。如同在开篇文章中一样，我将此次检索收集到的信息归类为黏膜靶向、器官和/或组织靶向、肿瘤靶向及局部递送等领域。本文所述的专利申请代表了这些领域的部分工作，尤其关注了一些更新颖或有趣的权利要求。
