Bellussi A, Miele V, Galluzzo M, Valenti M
Servizio di Radiologia dei Nuovi Padiglioni, Ospedale S. Camillo, Roma.
Radiol Med. 1997 Dec;94(6):579-82.
Craniostenosis is a complex association of syndromes and isolated diseases characterized by premature closure of cranial sutures. Three-dimensional (3D) Computed Tomography (CT) reconstructions have been widely used for years in the preoperative assessment and postoperative follow-up of craniostenosis, because of their effectiveness and diagnostic accuracy. Our study concerns the acquisition and reconstruction techniques of spiral CT images. This technique provides optimal diagnostic results allowing reduction of the radiation dose to the patient and of the sedation time.
May, 1995, to September, 1996, twelve patients with abnormal cranial growth or suspected craniostenosis underwent spiral CT examinations, with 3D reconstructions. Fourteen examinations were performed, including two postoperative investigations. Our diagnostic protocol consisted of images with 3 mm slice thickness, 3 mm slice interval, 2 s scan time, with 180 mAs, 120 kV. The images were reconstructed at 1 mm intervals.
According to the literature, this technique is safe enough relative to the dose to the patient (12.2 mSv) and permits to obtain good quality 3D reconstructions and adequate images of the brain and liquor spaces. Simple sedation was sufficient in all cases, using pentobarbital, 2-3 mg/kg.
The Authors emphasize the diagnostic effectiveness and accuracy of spiral CT with 3D reconstruction in the study of craniostenosis, which also permits imaging of the brain and liquor spaces with minimal loss of information.
颅缝早闭是一种复杂的综合征和孤立疾病的组合，其特征为颅骨缝过早闭合。三维（3D）计算机断层扫描（CT）重建技术多年来已广泛应用于颅缝早闭的术前评估和术后随访，因其有效性和诊断准确性。我们的研究涉及螺旋CT图像的采集和重建技术。该技术能提供最佳诊断结果，同时可减少患者所受辐射剂量及镇静时间。
1995年5月至1996年9月，12例颅骨生长异常或疑似颅缝早闭的患者接受了螺旋CT检查及3D重建。共进行了14次检查，包括2次术后检查。我们的诊断方案包括层厚3mm、层间距3mm、扫描时间2s、管电流180mAs、管电压120kV的图像，图像以1mm间隔重建。
根据文献，该技术相对于患者所受剂量（12.2mSv）足够安全，且能获得高质量的3D重建图像以及脑和脑脊液间隙的充分图像。在所有病例中，使用戊巴比妥2 - 3mg/kg进行简单镇静就足够了。
作者强调螺旋CT三维重建在颅缝早闭研究中的诊断有效性和准确性，它还能在信息损失最小的情况下对脑和脑脊液间隙进行成像。
