Drayer D, Kluger J, Reidenberg M, Lahita R
Drug Metab Rev. 1979;10(2):239-46. doi: 10.3109/03602537908997471.
In conclusion, it was the differential responses of slow and rapid acetylators to procainamide therapy that gave the initial clues that acetylprocainamide might be a safer drug than procainamide. So far, the experience with acetylprocainamide has been encouraging.
总之,正是慢乙酰化者和快乙酰化者对普鲁卡因胺治疗的不同反应,最初提示乙酰普鲁卡因胺可能是一种比普鲁卡因胺更安全的药物。到目前为止,使用乙酰普鲁卡因胺的经验一直令人鼓舞。