Brandes A, Carollo C, Gardiman M, Scelzi E, Bottin R, Zampieri P, Rigon A, Fiorentino M V
Department of Medical Oncology, Azienda Ospedaliera, Padova, Italy.
J Neurooncol. 1998 Jan;36(2):179-83. doi: 10.1023/a:1005708107153.
We describe a case of glioblastoma treated with chemoradiotherapy that spread to the dura mater with direct invasion of the skull base, protrusion into the homolateral nasal fossa, and penetrated of the frontal sinus, the orbital wall and the ethmoidal sinuses. Only eight cases of glioblastoma showing this development have been described in the literature; one of these, however, had a sarcomatous component which was absent in our case.
我们描述了一例接受放化疗的胶质母细胞瘤病例，该肿瘤扩散至硬脑膜，直接侵犯颅底，突入同侧鼻窝，并穿透额窦、眶壁和筛窦。文献中仅报道过8例出现这种进展的胶质母细胞瘤病例；然而，其中1例有肉瘤成分，而我们的病例没有。
