Hext P M, Richards R J
Br J Exp Pathol. 1976 Jun;57(3):281-5.
The ability of different types of asbestiform minerals to enhance or suppress the levels of fibrous collagen in cultures of lung fibroblasts was tested. All commercially important asbestos dusts produced both effects, a lower dose favouring a fibrogenic response whereas a higher dose favoured an opposite effect.
测试了不同类型的石棉状矿物增强或抑制肺成纤维细胞培养物中纤维状胶原蛋白水平的能力。所有具有商业重要性的石棉粉尘都产生了这两种效应,较低剂量有利于促纤维化反应,而较高剂量则有利于相反的效应。