Trichopoulos D, Handanos N, Danezis J, Kalandidi A, Kalapothaki V
Br J Obstet Gynaecol. 1976 Aug;83(8):645-50. doi: 10.1111/j.1471-0528.1976.tb00904.x.
The role of induced (and spontaneous) abortions in the aetiology of secondary sterility was investigated. Obstetric and gynaecologic histories were obtained from 100 women with secondary infertility admitted to the First Department of Obstetrics and Gynaecology of the University of Athens Medical School and to the Division of Fertility and Sterility of that Department. For every patient, an attempt was made to find two healthy control subjects from the same hospital with matching for age, parity, and level of education. Two control subjects each were found for 83 of the index patinets. The relative risk of secondary infertility among women with at least one induced abortion and no spontaneous abortions was 3.4 times that among women without any induced or spontaneous abortions (95 per cent confidence interval 1.38-8.37). The relationship was statistically significant and indicated that in Greece, about 45 per cent of the cases of secondary infertility may be attributable to previous induced abortions.
研究了人工流产（及自然流产）在继发性不孕病因中的作用。从雅典大学医学院第一妇产科及该科生育与不育科收治的100例继发性不孕妇女中获取了产科和妇科病史。对每例患者，试图从同一家医院找到两名年龄、产次和教育程度相匹配的健康对照者。83例索引患者中，每例均找到了两名对照者。至少有一次人工流产且无自然流产的妇女继发性不孕的相对风险是无任何人工流产或自然流产妇女的3.4倍（95%置信区间1.38 - 8.37）。这种关系具有统计学意义，表明在希腊，约45%的继发性不孕病例可能归因于既往人工流产。
