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[质量与生活方式作为急性脑血管疾病的危险因素]

[Quality and life style as risk factors in acute cerebrovascular disease].

作者信息

Peris A, Martín-González R, Valiente E, Ruiz A, Vioque J

机构信息

Departamento de Medicina y Psiquiatría, Universidad Miguel Hernández, San Juan, Alicante, España.

出版信息

Rev Neurol. 1997 Dec;25(148):1866-71.

PMID:9528019
Abstract

INTRODUCTION

In some series of patients with acute cerebral vascular disease (CVD) it has been seen that, prior to the episode of CVD, the patients already had a poorer quality of life than other people of their age. The object of this study is to evaluate their previous life style and quality of life as risk factors (RF) in acute CVD.

MATERIAL AND METHODS

A case-control study was done of a total of 151 patients admitted to two hospitals with acute CVD and 151 persons, who were not hospitalized and acted as the control group, paired (one to one) for age, sex and hospital. In both groups data were collected regarding basic general health, previous quality of life (Nottingham Health Profile-NHP-, life style and self-perception of social support. The relative risks were estimated by calculating the odds ratios and conditional logistic regression.

RESULTS

Regular moderate physical exercise acts as a protective factor with an OR of 0.32 (IC 95%: 0.14-0.76). Consumption of tobacco and alcohol increased the risk of CVD but did not reach statistical significance. No relationship was found between perceived social support and risk of CVD. Physical mobility, evaluated using the NHP showed a statistically significant negative association with acute CVD (OR: 0.32; IC 95%: 0.14-0.71).

CONCLUSIONS

Our results seem to suggest that the previous overall quality of life cannot be considered a RF in acute CVD, except for physical mobility as evaluated on the NHP. Reduction of this constitutes a RF and moderate physical exercise behaves as a protective factor.

摘要

引言

在一些急性脑血管疾病(CVD)患者系列研究中发现,在CVD发作之前,这些患者的生活质量就已经比同龄人差。本研究的目的是评估他们之前的生活方式和生活质量作为急性CVD的危险因素(RF)。

材料与方法

对两家医院收治的151例急性CVD患者和151名未住院的对照人员进行病例对照研究,对照人员按年龄、性别和医院进行一对一配对。收集两组关于基本总体健康状况、既往生活质量(诺丁汉健康量表-NHP-)、生活方式和社会支持自我认知的数据。通过计算比值比和条件逻辑回归来估计相对风险。

结果

定期适度体育锻炼起到保护作用,比值比为0.32(95%置信区间:0.14 - 0.76)。吸烟和饮酒会增加CVD风险,但未达到统计学显著性。未发现感知到的社会支持与CVD风险之间存在关联。使用NHP评估的身体活动能力与急性CVD呈统计学显著负相关(比值比:0.32;95%置信区间:0.14 - 0.71)。

结论

我们的结果似乎表明,除了通过NHP评估的身体活动能力外,既往总体生活质量不能被视为急性CVD的危险因素。身体活动能力降低构成一个危险因素,而适度体育锻炼起到保护作用。

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