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圆锥角膜的病因。

Aetiology of keratoconus.

作者信息

Karseras A G, Ruben M

出版信息

Br J Ophthalmol. 1976 Jul;60(7):522-5. doi: 10.1136/bjo.60.7.522.

DOI:10.1136/bjo.60.7.522
PMID:952827
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1017543/
Abstract

Keratoconus has a common association with atopic conditions. Most keratoconus patients rub their eyes excessively. Eye-rubbing is considered the dominant aetiological factor in two-thirds of patients with keratoconus who progress to contact lens wear. A classification of keratoconus based on the dominant aetiological factors is proposed. No significant psychoneurotic factor was found in the keratoconus patients compared with patients in the control group.

摘要

圆锥角膜与特应性疾病常有关联。大多数圆锥角膜患者会过度揉眼。在三分之二进展到需要佩戴角膜接触镜的圆锥角膜患者中,揉眼被认为是主要的病因学因素。本文提出了一种基于主要病因学因素的圆锥角膜分类方法。与对照组患者相比,未在圆锥角膜患者中发现显著的精神神经因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/316f/1017543/1ca06c6fde0f/brjopthal00247-0037-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/316f/1017543/f98fa43c5ded/brjopthal00247-0037-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/316f/1017543/1ca06c6fde0f/brjopthal00247-0037-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/316f/1017543/f98fa43c5ded/brjopthal00247-0037-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/316f/1017543/1ca06c6fde0f/brjopthal00247-0037-b.jpg

相似文献

1
Aetiology of keratoconus.圆锥角膜的病因。
Br J Ophthalmol. 1976 Jul;60(7):522-5. doi: 10.1136/bjo.60.7.522.
2
Atopy and keratoconus: a multivariate analysis.特应性与圆锥角膜:多变量分析
Br J Ophthalmol. 2000 Aug;84(8):834-6. doi: 10.1136/bjo.84.8.834.
3
Eye rubbing type and prevalence including contact lens 'removal-relief' rubbing.揉眼类型及患病率,包括隐形眼镜“摘除-缓解”性揉眼。
Clin Exp Optom. 2016 Jul;99(4):366-72. doi: 10.1111/cxo.12343. Epub 2016 Jun 16.
4
Keratoconus, allergy, itch, eye-rubbing and hand-dominance.圆锥角膜、过敏、瘙痒、揉眼与用手习惯。
Clin Exp Optom. 2003 Nov;86(6):376-84. doi: 10.1111/j.1444-0938.2003.tb03082.x.
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Abnormal rubbing and keratectasia.异常摩擦与角膜扩张。
Eye Contact Lens. 2007 Nov;33(6 Pt 1):265-71. doi: 10.1097/ICL.0b013e31814fb64b.
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Unilateral keratoconus in a child with chronic and persistent eye rubbing.一名患有慢性持续性揉眼的儿童的单侧圆锥角膜。
Am J Ophthalmol. 2005 Feb;139(2):356-7. doi: 10.1016/j.ajo.2004.07.044.
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Association between keratoconus and atopy.圆锥角膜与特应性之间的关联。
Br J Ophthalmol. 1989 Oct;73(10):816-22. doi: 10.1136/bjo.73.10.816.
8
Independent and interactive effects of eye rubbing and atopy on keratoconus.揉眼和特应性对圆锥角膜的独立和交互影响。
Front Immunol. 2022 Sep 29;13:999435. doi: 10.3389/fimmu.2022.999435. eCollection 2022.
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Corneal thickness, astigmatism, and atopy.角膜厚度、散光和特应性。
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Mechanisms of rubbing-related corneal trauma in keratoconus.圆锥角膜中与摩擦相关的角膜创伤机制。
Cornea. 2009 Jul;28(6):607-15. doi: 10.1097/ICO.0b013e318198384f.

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Prevalence of keratoconus and keratoconus suspect, and their characteristics on corneal tomography in a population-based study.一项基于人群的研究中圆锥角膜和疑似圆锥角膜的患病率及其在角膜地形图上的特征。
PLoS One. 2025 Jan 16;20(1):e0308892. doi: 10.1371/journal.pone.0308892. eCollection 2025.
2
Eye-Rubbing Detection Tool Using Artificial Intelligence on a Smartwatch in the Management of Keratoconus.在圆锥角膜管理中使用智能手表上的人工智能进行揉眼检测工具
Transl Vis Sci Technol. 2024 Dec 2;13(12):16. doi: 10.1167/tvst.13.12.16.
3
Recurrent keratoconus: an analysis of breaks in Bowman's layer in corneal grafts.

本文引用的文献

1
Contact lenses in treatment of keratoconus.角膜接触镜在圆锥角膜治疗中的应用
Br J Ophthalmol. 1956 May;40(5):295-304. doi: 10.1136/bjo.40.5.295.
2
Occurrence of cataracts and keratoconus with atopic dermatitis.
AMA Arch Derm. 1955 Sep;72(3):237-41. doi: 10.1001/archderm.1955.03730330017003.
复发性圆锥角膜:角膜移植物中 Bowman 层破裂的分析。
BMJ Open Ophthalmol. 2023 Apr;8(1). doi: 10.1136/bmjophth-2022-001225.
4
New Keratoconus Risk Factors: A Cross-Sectional Case-Control Study.圆锥角膜新的危险因素:一项横断面病例对照研究。
J Ophthalmol. 2022 Sep 28;2022:6605771. doi: 10.1155/2022/6605771. eCollection 2022.
5
Complications of accelerated corneal collagen cross-linking: review of 2025 eyes.加速角膜胶原交联术的并发症:2025 只眼的回顾。
Int Ophthalmol. 2020 Dec;40(12):3269-3277. doi: 10.1007/s10792-020-01512-3. Epub 2020 Jul 26.
6
Genetic Aspects of Keratoconus: A Literature Review Exploring Potential Genetic Contributions and Possible Genetic Relationships with Comorbidities.圆锥角膜的遗传学方面:一篇文献综述,探讨潜在的遗传贡献以及与合并症可能的遗传关系。
Ophthalmol Ther. 2018 Dec;7(2):263-292. doi: 10.1007/s40123-018-0144-8. Epub 2018 Sep 6.
7
Molecular and Histopathological Changes Associated with Keratoconus.与圆锥角膜相关的分子和组织病理学变化
Biomed Res Int. 2017;2017:7803029. doi: 10.1155/2017/7803029. Epub 2017 Jan 30.
8
Endocrine and Metabolic Pathways Linked to Keratoconus: Implications for the Role of Hormones in the Stromal Microenvironment.与圆锥角膜相关的内分泌和代谢途径:对激素在基质微环境中作用的启示。
Sci Rep. 2016 May 9;6:25534. doi: 10.1038/srep25534.
9
Comparison of Scheimpflug imaging parameters between steep and keratoconic corneas of Caucasian eyes.白种人眼睛陡峭角膜与圆锥角膜的眼前节分析系统成像参数比较。
Clin Ophthalmol. 2016 Apr 1;10:603-8. doi: 10.2147/OPTH.S102683. eCollection 2016.
10
Collagen cross-linking effect on progressive keratoconus in patients younger than 18 years of age: A clinical trial.胶原蛋白交联对18岁以下圆锥角膜患者病情进展的影响:一项临床试验。
Adv Biomed Res. 2015 Nov 23;4:245. doi: 10.4103/2277-9175.170240. eCollection 2015.