奥氮平致死性过量服用。

Fatal overdose of olanzepine.

作者信息

Elian A A

机构信息

Commonwealth of Massachusetts, Forensic Toxicology Laboratory, Sudbury, MA 01776, USA.

出版信息

Forensic Sci Int. 1998 Feb 16;91(3):231-5. doi: 10.1016/s0379-0738(97)00195-3.

DOI:10.1016/s0379-0738(97)00195-3

PMID:9530833

Abstract

An ingestion of an unknown quantity of Zyprexa (olanzapine) tablets in a suicide is described. Biological fluid samples obtained at autopsy were analyzed for the presence of olanzapine by gas chromatography equipped with nitrogen-phosphorous detector and gas chromatography/mass spectroscopy. The blood concentration of olanzapine was 490 micrograms/dl and the concentration in gastric contents was 4100 micrograms/dl.

摘要

描述了一起自杀事件中摄入未知数量的再普乐（奥氮平）片的情况。对尸检时获取的生物流体样本，采用配备氮磷检测器的气相色谱法以及气相色谱/质谱联用技术分析其中奥氮平的存在情况。奥氮平的血液浓度为490微克/分升，胃内容物中的浓度为4100微克/分升。