Anteyi E A, Idoko J A, Ukoli C O, Bello C S
Department of Medicine, Jos University Teaching Hospital, Nigeria.
Afr J Med Med Sci. 1996 Dec;25(4):317-21.
A study of determine the seroprevalence rate and clinical presentation of HIV-associated pulmonary tuberculosis was carried out in Jos between October 1990 and September 1991. Out of the 180 newly diagnosed pulmonary tuberculosis patients, 11(6.1%) were confirmed seropositive for HIV-1 and 2. The peak age range for both tuberculosis and HIV infection in both sexes is 20-40 years. The risk of HIV infection was associated with multiple sex partners and blood transfusion. There was no significant difference in the clinical presentation of pulmonary tuberculosis between HIV-seropositive and seronegative patients (P > 0.1). However, diarrhoea, lymphadenopathy and marked weight loss were found to be significantly associated with HIV infection (P < 0.05). The mean lymphocyte count of HIV seropositives was significantly lower than seronegatives (P < 0.01).
1990年10月至1991年9月期间，在乔斯开展了一项关于确定HIV相关肺结核血清阳性率和临床表现的研究。在180例新诊断的肺结核患者中，11例（6.1%）被确诊为HIV-1和HIV-2血清阳性。男女患肺结核和HIV感染的高峰年龄范围均为20至40岁。HIV感染风险与多个性伴侣及输血有关。HIV血清阳性和血清阴性患者的肺结核临床表现无显著差异（P>0.1）。然而，腹泻、淋巴结病和明显体重减轻被发现与HIV感染显著相关（P<0.05）。HIV血清阳性者的平均淋巴细胞计数显著低于血清阴性者（P<0.01）。
