Skurkovich S V, Kalinina I A, Eremkina E I, Bulycheva T I
Biull Eksp Biol Med. 1976 Jun;81(6):706-7.
A single intraperitioneal injection of L 1210 cells preincubated in interferon or in "false interferon" was given to mice. These mice were sacrificed on the 10th day, and cytotoxicity of the sera against the L 1210 leukemic cells vas determined in the microcytotoxic test (modification of Terasaki's method). Leukemic cells treated with interferon before the immunization caused a more pronounced immune response in comparison with the cells treated under the same conditions with "false interferon". By the results of cytotoxic reaction immune response was enhanced 2-4-fold.
给小鼠单次腹腔注射预先在干扰素或“假干扰素”中孵育过的L1210细胞。在第10天处死这些小鼠，并在微量细胞毒性试验（对寺崎方法的改良）中测定血清对L1210白血病细胞的细胞毒性。与在相同条件下用“假干扰素”处理的细胞相比，免疫前用干扰素处理的白血病细胞引起了更明显的免疫反应。根据细胞毒性反应的结果，免疫反应增强了2至4倍。
