Kalashnikov V V, Borisenko S A, Tatarinov I S
Biull Eksp Biol Med. 1976 Jun;81(6):725-6.
A new embryonic antigen was found in the ovarian tumour tissues by immunodiffusion methods. This antigen consists of two components with a different electrophoretic mobility: a low peak migrates in the alha0-globulin zone, and a rapid one - in the prealbumin zone; it differs immunologically from alpha-fetoprot ein and cancer embrynoic antigen of the large intestine. This antigen was found in the fetus and newborn blood serum and also in the tissue extracts of ovarian tumours. No such antigen was revealed in the normal tissues of adults, or in the blood serum of donors and oncological patients.
通过免疫扩散法在卵巢肿瘤组织中发现了一种新的胚胎抗原。该抗原由两种具有不同电泳迁移率的成分组成：一个低峰在α0-球蛋白区迁移，另一个快速峰在前白蛋白区迁移；它在免疫学上与甲胎蛋白和大肠癌胚抗原不同。这种抗原在胎儿和新生儿血清以及卵巢肿瘤的组织提取物中均有发现。在成人的正常组织、供体和肿瘤患者的血清中未发现这种抗原。
