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[下丘脑切除及去传入神经后创伤性休克大鼠的肾上腺皮质功能]

[Adrenal cortical function in rats with traumatic shock following removal and deafferentation of the hypothalamus].

作者信息

Mazurkevich G S, Kulikova N A

出版信息

Biull Eksp Biol Med. 1976 Jul;82(7):785-7.

PMID:953331
Abstract

The 11-oxycorticosteroid (11-OCS) content was studied in the blood plasma of sham-operated rats, rats with intact, ablated and deafferentated medial-basal hypothalamus (MBH) in traumatic shock. There were no reliable differences in the 11-OCS basal level in various groups of rats. MBH ablation led to the reduction in the weight of adrenal and pituitary glands and MBH deafferentation -- to increase in the weight of the former. The 11-OCS level was reliably higher in traumatic shock of rats with complete MBH deafferentation than in sham-operated animals.

摘要

研究了假手术大鼠、下丘脑内侧基底部(MBH)完整、切除及传入神经切断的大鼠在创伤性休克时血浆中11-氧皮质类固醇(11-OCS)的含量。各实验组大鼠的11-OCS基础水平无显著差异。切除MBH导致肾上腺和垂体重量减轻,而切断MBH传入神经则导致肾上腺重量增加。完全切断MBH传入神经的大鼠在创伤性休克时的11-OCS水平显著高于假手术动物。

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