Micieli G, Bosone D, Marcheselli S, Cavallini A, Rossi F, Nappi G
Department of Neurology, IRCCS, C. Mondino Foundation, University of Pavia, Italy.
Cephalalgia. 1998 Feb;18 Suppl 21:17-22. doi: 10.1177/0333102498018s2105.
This paper is an extensive review of the use of transcranial Doppler (TCD) devices in "vascular" forms of headache, and a discussion of the possible occurrence of nonunivocal results, particularly in migraine with or without aura. Despite the large variability in findings, TCD is a noninvasive, safe, and reproducible method for studying hemodynamic phenomena which characterize the clinical profile of migraine and cluster headache attacks. Similarly, it can detect cerebrovasomotor reactivity to external/internal environmental stimuli, as well as responses to pharmacological (therapeutic or diagnostic) agents. Possible future applications of TCD in monitoring vasomotor changes in response to selective stimuli (sympathetic, neuropeptidergic, etc.) are also considered.
本文是对经颅多普勒（TCD）设备在“血管性”头痛形式中的应用的广泛综述，并讨论了可能出现的不明确结果，特别是在有或无先兆的偏头痛中。尽管研究结果差异很大，但TCD是一种用于研究血流动力学现象的非侵入性、安全且可重复的方法，这些现象是偏头痛和丛集性头痛发作临床特征的表征。同样，它可以检测脑血管对外部/内部环境刺激的反应性，以及对药物（治疗或诊断）制剂的反应。还考虑了TCD未来在监测对选择性刺激（交感神经、神经肽能等）的血管运动变化方面的可能应用。
