Strüder H K, Hollmann W, Platen P, Rost R, Weicker H, Weber K
Institute of Sports Games, German Sport University, Cologne.
Eur J Appl Physiol Occup Physiol. 1998 Feb;77(3):285-8. doi: 10.1007/s004210050334.
The aim of this study was to investigate hypothalamic-pituitary-adrenal (HPAA) and -gonadal (HPGA) axis responses to post-exercise (30 min at 65% VO2max) combined corticotrophin, luteinizing hormone and thyrotrophin releasing hormone challenge (0.7 microg/ kg body mass) in elderly distance runners (DR; age: 68.9+/-4.2 year) and sedentary individuals (SI; age: 69.1+/-2.6 year). Plasma cortisol, growth hormone, prolactin, luteinizing hormone, follicle stimulating hormone and total testosterone (T) concentrations pre- and post-exercise as well as in response to stimulation did not differ between DR and SI. Plasma adrenocorticotropic hormone returned to pre-exercise level in DR 60 min and in SI 90 min post-stimulation. Free T was lower in DR at all time points. Our results do not support the notion of altered releasing hormone-stimulable HPAA and HPGA synthesis-secretion capacity in elderly males after endurance training.
本研究旨在调查老年长跑运动员（DR；年龄：68.9±4.2岁）和久坐不动者（SI；年龄：69.1±2.6岁）下丘脑-垂体-肾上腺（HPAA）轴和下丘脑-垂体-性腺（HPGA）轴对运动后（以65%最大摄氧量运动30分钟）联合促肾上腺皮质激素、黄体生成素和促甲状腺激素释放激素刺激（0.7微克/千克体重）的反应。长跑运动员和久坐不动者运动前后以及刺激后血浆皮质醇、生长激素、催乳素、黄体生成素、卵泡刺激素和总睾酮（T）浓度无差异。刺激后60分钟，长跑运动员血浆促肾上腺皮质激素恢复到运动前水平，久坐不动者则在90分钟恢复到运动前水平。长跑运动员在所有时间点的游离睾酮均较低。我们的研究结果不支持耐力训练后老年男性促释放激素刺激的HPAA和HPGA合成-分泌能力改变的观点。
