Watkins L M, Remulla H D, Rubin P A
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA.
Am J Ophthalmol. 1997 Jun;123(6):854-6. doi: 10.1016/s0002-9394(14)71146-8.
To report a 71-year-old woman with acute myelogenous leukemia in remission who developed orbital granulocytic sarcoma.
The patient was referred for acute proptosis and decreased vision of the right eye. Computed tomography of the orbits demonstrated a right extraconal mass compressing the optic nerve. A right lateral orbitotomy was performed, and a portion of the mass was excised for diagnostic purposes and orbital decompression.
Histopathologic and immunohistochemical evaluation disclosed orbital granulocytic sarcoma. With chemotherapy and radiation, vision remained stable and right proptosis resolved.
Orbital granulocytic sarcoma is usually diagnosed in children with a history of acute myelogenous leukemia. This case demonstrated that this entity may also occur rarely in older patients with a history of acute myelogenous leukemia.
报告一名71岁处于缓解期的急性髓系白血病女性患者，其发生了眼眶粒细胞肉瘤。
该患者因右眼急性眼球突出和视力下降前来就诊。眼眶计算机断层扫描显示右侧肌锥外肿块压迫视神经。进行了右侧眼眶外侧切开术，切除部分肿块用于诊断和眼眶减压。
组织病理学和免疫组化评估显示为眼眶粒细胞肉瘤。经过化疗和放疗，视力保持稳定，右眼眼球突出得到缓解。
眼眶粒细胞肉瘤通常在有急性髓系白血病病史的儿童中被诊断出来。本病例表明，这种情况在有急性髓系白血病病史的老年患者中也可能罕见发生。
