Potter S, Yang X, Boulanger M J, Ishiguro E E
Department of Biochemistry and Microbiology, University of Victoria, British Columbia, Canada.
J Bacteriol. 1998 Apr;180(7):1959-61. doi: 10.1128/JB.180.7.1959-1961.1998.
The Escherichia coli LytB protein regulates the activity of guanosine 3',5'-bispyrophosphate synthetase I (RelA). A Southern blot analysis of chromosomal DNA with the E. coli lytB gene as a probe revealed the presence of lytB homologs in all of the gram-negative bacterial species examined but not in gram-positive species. The lytB homologs from Enterobacter aerogenes and Pseudomonas fluorescens complemented the E. coli lytB44 mutant allele.
大肠杆菌LytB蛋白调节鸟苷3',5'-双焦磷酸合成酶I（RelA）的活性。用大肠杆菌lytB基因作为探针进行染色体DNA的Southern印迹分析表明，在所检测的所有革兰氏阴性细菌物种中都存在lytB同源物，而在革兰氏阳性物种中则不存在。产气肠杆菌和荧光假单胞菌的lytB同源物可互补大肠杆菌lytB44突变等位基因。
