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轻微头部损伤后矢状窦血栓形成,采用持续尿激酶输注治疗。

Sagittal sinus thrombosis following minor head injury treated with continuous urokinase infusion.

作者信息

D'Alise M D, Fichtel F, Horowitz M

机构信息

Department of Neurosurgery, University of Texas Southwestern Medical Center at Dallas, 75235-8855, USA.

出版信息

Surg Neurol. 1998 Apr;49(4):430-5. doi: 10.1016/s0090-3019(97)00182-1.

DOI:10.1016/s0090-3019(97)00182-1
PMID:9537663
Abstract

BACKGROUND

Cerebral dural sinus thrombosis is a rare clinical entity. Symptoms may be vague, and left untreated thrombus progression may be fatal because of venous congestion and infarction.

METHODS

We report a case of post-traumatic dural sinus thrombosis treated with selective transfemoral, transvenous catheterization and infusion of urokinase.

RESULTS

Urokinase infusion into the dural venous sinuses using a microcatheter introduced from the femoral vein was successfully carried out, and patency of the venous sinuses was reestablished.

CONCLUSION

Venous sinus thrombosis can be an overlooked sequel to head injury. If the diagnosis is entertained, prompt performance of appropriate imaging studies should be instituted so that therapy can be initiated. The use of selective sinus catheterization using microcatheter techniques with instillation of urokinase is an excellent mode of therapy that should be considered in any patient with symptomatic occlusion.

摘要

背景

脑硬膜窦血栓形成是一种罕见的临床病症。症状可能不明确,若不治疗,由于静脉淤血和梗死,血栓进展可能会致命。

方法

我们报告一例创伤后脑硬膜窦血栓形成的病例,采用经股静脉选择性经静脉导管插入术并注入尿激酶进行治疗。

结果

通过从股静脉引入的微导管成功地将尿激酶注入硬脑膜静脉窦,静脉窦恢复通畅。

结论

静脉窦血栓形成可能是头部损伤被忽视的后遗症。如果考虑到该诊断,应及时进行适当的影像学检查以便开始治疗。使用微导管技术进行选择性窦导管插入术并注入尿激酶是一种很好的治疗方式,任何有症状性闭塞的患者都应考虑采用。

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Sagittal sinus thrombosis following minor head injury treated with continuous urokinase infusion.轻微头部损伤后矢状窦血栓形成,采用持续尿激酶输注治疗。
Surg Neurol. 1998 Apr;49(4):430-5. doi: 10.1016/s0090-3019(97)00182-1.
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[A case report of dural sinus thrombosis: direct thrombolytic therapy using endovascular surgery].[硬脑膜窦血栓形成病例报告:采用血管内手术的直接溶栓治疗]
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