经食管超声心动图对胆固醇栓塞中胸主动脉的研究。
Investigation of the thoracic aorta in cholesterol embolism by transoesophageal echocardiography.
作者信息
Ferrari E, Taillan B, Drai E, Morand P, Baudouy M
机构信息
Department of Cardiology, Hôpital Pasteur, Nice, France.
出版信息
Heart. 1998 Feb;79(2):133-6. doi: 10.1136/hrt.79.2.133.
OBJECTIVES
To examine the thoracic aorta of patients with severe cholesterol embolism (CE) by transoesophageal echocardiography (TOE).
METHODS
The thoracic aorta of 20 consecutive patients with CE was compared with that in a control population matched for age and risk factors by TOE. Patients were prescribed steroids after CE was diagnosed. Follow up is reported and compared with results in the literature.
RESULTS
Aortic plaques and debris were more common in patients with CE than in the control population (p < 0.001 and p < 0.0001, respectively). The mean (SD) number of aortic plaques in the CE patients was 2.6 (0.7). This aortic atheroma was found predominantly in the descending aorta. One patient died during a mean (SD) follow up of 24 (10) months.
CONCLUSIONS
Aortic atheroma, as detected by TOE, should be considered as the main source of CE. In addition, the prognosis in our series, in which steroids were systemically prescribed, is much better than in others reported in the literature.
目的
通过经食管超声心动图（TOE）检查严重胆固醇栓塞（CE）患者的胸主动脉。
方法
通过TOE将20例连续的CE患者的胸主动脉与年龄和危险因素相匹配的对照人群的胸主动脉进行比较。CE诊断后给患者使用类固醇。报告随访情况并与文献中的结果进行比较。
结果
CE患者的主动脉斑块和碎片比对照人群更常见（分别为p < 0.001和p < 0.0001）。CE患者主动脉斑块的平均（标准差）数为2.6（0.7）。这种主动脉粥样硬化主要见于降主动脉。在平均（标准差）24（10）个月的随访期间有1例患者死亡。
结论
TOE检测到的主动脉粥样硬化应被视为CE的主要来源。此外，在我们系统性使用类固醇的系列研究中，预后比文献中报道的其他研究要好得多。
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