Tenenbaum A, Garniek A, Shemesh J, Fisman E Z, Stroh C I, Itzchak Y, Vered Z, Motro M
Department of Diagnostic Imaging, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Radiology. 1998 Jul;208(1):153-8. doi: 10.1148/radiology.208.1.9646807.
To investigate whether unenhanced dual-helical computed tomography (CT) is useful in the rapid, noninvasive detection of protruding aortic atheromas.
Thirty-two consecutive patients at least 50 years of age who had recent ischemic stroke, systemic emboli, or both, underwent transesophageal echocardiography (TEE) and unenhanced dual-helical CT with thin sections (section thickness, 3.2 mm; reconstruction increment, 1.5 mm).
TEE demonstrated protruding aortic atheromas 15 patients (47%); dual-helical CT depicted protruding aortic atheromas in 13 of those 15 patients (87%). Of the 17 patients without a protruding aortic atheroma at TEE, dual-helical CT helped confirm the absence in 14 (82%). Dual-helical CT yielded a sensitivity of 87%, a specificity of 82%, and an overall accuracy of 84%. Thirty-six protruding plaques were detected with TEE, of which 34 (94%) were correctly identified with dual-helical CT. Of those 34 plaques, 27 (79%) contained variable amounts of calcium and seven (21%) showed hypoattenuation suggestive of soft plaques and thrombi. In six patients, dual-helical CT depicted a protruding aortic atheroma between the distal ascending aorta and the proximal arch; these plaques were not included in the comparative statistics and were analyzed separately.
Unenhanced dual-helical CT with thin sections appears to be useful for the rapid, noninvasive detection of a protruding aortic atheroma, especially in areas not clearly visualized with TEE.
探讨非增强双螺旋计算机断层扫描(CT)在快速、无创检测突出型主动脉粥样硬化斑块方面是否有用。
连续32例年龄至少50岁、近期有缺血性脑卒中、系统性栓塞或两者皆有的患者接受了经食管超声心动图(TEE)检查及非增强双螺旋薄层CT扫描(层厚3.2mm;重建间隔1.5mm)。
TEE显示15例患者(47%)有突出型主动脉粥样硬化斑块;双螺旋CT在这15例患者中的13例(87%)显示有突出型主动脉粥样硬化斑块。在TEE检查未发现突出型主动脉粥样硬化斑块的17例患者中,双螺旋CT帮助证实其中14例(82%)确实没有。双螺旋CT的敏感性为87%,特异性为82%,总体准确率为84%。TEE检测到36个突出斑块,其中34个(94%)被双螺旋CT正确识别。在这34个斑块中,27个(79%)含有不同量的钙,7个(21%)表现为低密度,提示为软斑块和血栓。6例患者中,双螺旋CT显示在升主动脉远端和主动脉弓近端之间有突出型主动脉粥样硬化斑块;这些斑块未纳入比较统计,而是单独进行分析。
非增强双螺旋薄层CT似乎有助于快速、无创检测突出型主动脉粥样硬化斑块,尤其是在TEE不能清晰显示的区域。