男性化颗粒细胞瘤

Wilansky D L, Scott B H, Lachance R C

Can Med Assoc J. 1976 Sep 18;115(6):545-6.

A 23-year-old woman had oligomenorrhea, underdevelopment of the breasts, moderate hirsutism and increased serum testosterone values associated with a benign noncystic granulosa cell tumour of the left ovary. She was frail, irritable and apathetic. Since the age of 7 she had had periodic abdominal pain with nausea, vomiting and dizziness; irritability and occipital headache appeared when she was older. Her symptoms resolved and the masculinization did not progress after the tumour was removed. Only six similar well documented cases have been reported.

一名23岁女性出现月经过少、乳房发育不全、中度多毛以及血清睾酮值升高，伴有左侧卵巢良性非囊性颗粒细胞瘤。她身体虚弱、易怒且冷漠。自7岁起，她就周期性地出现腹痛，并伴有恶心、呕吐和头晕；长大后出现易怒和枕部头痛。肿瘤切除后，她的症状消失，男性化表现也未进一步发展。此前仅报道过6例类似的详细记录病例。