颌骨软骨黏液样纤维瘤。病例报告及文献复习

Chondromyxoid fibroma of the jaws. Case report and review of the literature.

作者信息

Hammad H M, Hammond H L, Kurago Z B, Frank J A

机构信息

Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, USA.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 Mar;85(3):293-300. doi: 10.1016/s1079-2104(98)90011-7.

DOI:10.1016/s1079-2104(98)90011-7

PMID:9540086

Abstract

Chondromyxoid fibroma is a benign tumor of bone that is characterized by chondroid and myxoid differentiation and by ultrastructural and immunohistochemical evidence of chondral origin. It is rare in the jaws and skull bones, where only about 2% of all cases have been reported. A review of the 20 acceptable gnathic cases in the literature and of the current case revealed both a higher incidence in the mandible (76%) than in the maxilla (24%) and an equal sex distribution. The sites of occurrence in both jaws are compatible with origin from developmental cartilaginous remnants. The controversies regarding malignant transformation and therapeutic approach are addressed.

摘要

软骨黏液样纤维瘤是一种骨的良性肿瘤，其特征为软骨样和黏液样分化以及有软骨起源的超微结构和免疫组织化学证据。它在颌骨和颅骨中罕见，在所有病例中仅有约2%的病例有报道。对文献中20例可接受的颌骨病例以及当前病例的回顾显示，下颌骨（76%）的发病率高于上颌骨（24%），且性别分布均等。上下颌骨的发病部位与发育性软骨残余起源相符。文中还讨论了关于恶性转化和治疗方法的争议。