McGregor C G, Bradley J F, McGee J O, Wheatley D J
Cardiovasc Res. 1976 May;10(3):394-7. doi: 10.1093/cvr/10.3.394.
Viability of antibiotic sterilized and stored human heart valves obtained at routine necropsy was assessed by tissue culture and protein and collagen synthesis. Only three of 23 valves examined showed any evidence of viability, in striking contrast to earlier work on canine valves obtained under optimal conditions. These findings justify doubts regarding pre-implantation viability in human heart valves prepared for grafting.
通过组织培养以及蛋白质和胶原蛋白合成，评估了在常规尸检时获取的经抗生素消毒并储存的人体心脏瓣膜的存活能力。在检查的23个瓣膜中，只有3个显示出任何存活能力的迹象，这与早期在最佳条件下获取的犬类瓣膜的研究结果形成了鲜明对比。这些发现使得人们对准备用于移植的人体心脏瓣膜植入前的存活能力产生怀疑。
