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Tissue culture, protein and collagen synthesis in antibiotic sterilized canine heart valves.

作者信息

McGregor C G, Bradley J F, McGee J O, Wheatley D J

出版信息

Cardiovasc Res. 1976 May;10(3):389-93. doi: 10.1093/cvr/10.3.389.

DOI:10.1093/cvr/10.3.389
PMID:954023
Abstract

Viability of canine heart valve leaflet fibroblasts was assessed after varying periods of sterilization and storage in antibiotic-nutrient solution. Tissue culture and assessment of protein and collagen synthesis showed that tissue obtained under optimal conditions rarely retains viability beyond 3 weeks in antibiotic-nutrient solution and is severely impaired after 2 weeks. This casts serious doubts on viability in current clinical homograft valve practice.

摘要

相似文献

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Tissue culture, protein and collagen synthesis in antibiotic sterilized canine heart valves.
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引用本文的文献

1
Morphology of heart valves preserved by liquid nitrogen freezing.
Thorax. 1985 Oct;40(10):778-86. doi: 10.1136/thx.40.10.778.
2
Determining viability of fresh or cryopreserved homograft valves at implantation.确定新鲜或冷冻保存的同种异体移植瓣膜在植入时的活力。
Heart Vessels. 1987;3(4):205-8. doi: 10.1007/BF02058312.