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[健康患者中由单核细胞增生李斯特菌引起的内源性眼内炎:以PCR辅助快速诊断为成功治疗的基础]

[Listeria monocytogenes-induced endogenous endophthalmitis in an otherwise healthy patient: PCR-assisted rapid diagnosis as the basis for successful therapy].

作者信息

Lohmann C P, Heep M, Linde H J, Reischl U

机构信息

Universitäts-Augenklinik, Franz-Josef-Straussallee.

出版信息

Klin Monbl Augenheilkd. 1998 Jan;212(1):55-8. doi: 10.1055/s-2008-1034832.

Abstract

BACKGROUND

Listeria monocytogenes is a rare cause of endogenous endophthalmitis. Only 14 cases are published in the literature so far. All eyes showed similar clinical features and profound visual loss.

PATIENTS AND METHODS

We report on a case of an otherwise healthy 73-year-old male. He was referred to our hospital because of acute hypopyoniritis with secondary glaucoma. Within a few hours the severity of the intraocular infection increased dramatically resulting in the clinical picture of an acute endophthalmitis.

RESULTS AND CONCLUSION

Early identification of the causative pathogen in the aqueous humor after anterior chamber paracenthesis using polymerase chain reaction (PCR) and the initiation of a specific, systemic antibiotic medication resulted in a complete recovery of visual acuity.

摘要

背景

单核细胞增生李斯特菌是内源性眼内炎的罕见病因。迄今为止,文献中仅报道了14例。所有病例的眼部均表现出相似的临床特征且视力严重丧失。

患者与方法

我们报告一例73岁健康男性病例。他因急性前房积脓性虹膜炎伴继发性青光眼转诊至我院。数小时内,眼内感染的严重程度急剧增加,导致急性眼内炎的临床表现。

结果与结论

在前房穿刺后,通过聚合酶链反应(PCR)早期鉴定房水中的致病病原体,并开始使用特异性全身抗生素治疗,使视力完全恢复。

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