Lohmann C P, Gabel V P, Heep M, Linde H J, Reischl U
University Eye Clinic, Regensburg, Germany.
Eur J Ophthalmol. 1999 Jan-Mar;9(1):53-7.
Listeria monocytogenes is a rare cause of endogenous endophthalmitis. To date 15 cases have been published in the literature. All eyes showed similar clinical features and profound visual loss mainly due to delayed diagnosis.
An additional case of an otherwise healthy 73 year-old male, who was referred to our hospital because of acute iridocyclitis with secondary glaucoma, is reported. Within a few days the severity of the intraocular infection increased dramatically, resulting in the clinical picture of acute endophthalmitis.
In contrast to most published cases, early identification of the causative pathogen in the aqueous humor after anterior chamber puncture using polymerase chain reaction (PCR) and the initiation of a specific, systemic antibiotic medication, resulted in-complete recovery of visual acuity.
PCR is very useful for the identification of the pathogen in intraocular infections.
单核细胞增生李斯特菌是内源性眼内炎的罕见病因。迄今为止，文献中已发表了15例病例。所有病例的眼部均表现出相似的临床特征，且主要由于诊断延迟导致严重视力丧失。
报告了另外1例原本健康的73岁男性病例，该患者因急性虹膜睫状体炎继发青光眼转诊至我院。在几天内，眼内感染的严重程度急剧增加，导致急性眼内炎的临床表现。
与大多数已发表的病例不同，通过聚合酶链反应（PCR）在前房穿刺后早期识别房水中的致病病原体，并开始使用特异性全身抗生素治疗，使视力完全恢复。
PCR对眼内感染病原体的鉴定非常有用。
