Lange U, Berliner M, Ludwig M, Schiefer H G, Teichmann J, Weidner W, Schmidt K L
Department of Rheumatology/University Giessen, Bad Nauheim, Germany.
Rheumatol Int. 1998;17(5):181-4. doi: 10.1007/s002960050031.
Thirty-two female patients with confirmed ankylosing spondylitis (AS) and 33 women of similar age with pure ileitis terminalis Crohn were examined for genitourinary infection. Urethral syndrome was found in 15 out of 32 patients with AS: 11 of them had urethritis and 4 urethritis associated with vaginitis. Five women of the control group suffered from urethritis. In all cases with genitourinary infection, Chlamydia trachomatis was isolated. By comparing the AS-patients (urogenital infection group and the non-infected group) with regard to other present clinical parameters, it was found, as expected, that the erythrocyte sedimentation rate in the 1st hour was significantly higher in the infected group. In addition, the infected patients had a significantly higher incidence of enthesopathy, involvement of the spinal column, and higher C-reactive protein values (CRP > or = 5 mg/l). A family history of AS was equally present. Other clinical parameters, such as inflammatory involvement of the joints and HLA-B27 correlation, did not differ significantly between infected and non-infected patients.
对32例确诊为强直性脊柱炎（AS）的女性患者和33例年龄相仿的单纯性末端回肠炎克罗恩病女性患者进行了泌尿生殖系统感染检查。在32例AS患者中，有15例发现有尿道综合征：其中11例患有尿道炎，4例尿道炎合并阴道炎。对照组中有5名女性患有尿道炎。在所有泌尿生殖系统感染病例中，均分离出沙眼衣原体。通过比较AS患者（泌尿生殖系统感染组和未感染组）的其他现有临床参数，不出所料地发现，感染组第1小时的红细胞沉降率明显更高。此外，感染患者的附着点病、脊柱受累发生率以及C反应蛋白值（CRP≥5mg/L）明显更高。AS家族史同样存在。感染患者和未感染患者之间的其他临床参数，如关节的炎症累及和HLA - B27相关性，没有显著差异。
