Foster B J, Duffy C M, Sharma A K
Montreal Children's Hospital, McGill University, Quebec, Canada.
Pediatr Nephrol. 1998 Feb;12(2):113-6. doi: 10.1007/s004670050416.
Systemic-onset juvenile rheumatoid arthritis (JRA) is a complex disease which affects many organ systems. Associated renal lesions are unusual, with the possible exception of amyloidosis. We describe a girl with systemic-onset JRA who developed first membranous nephropathy and then, 3.5 years later, a severe crescentic glomerulonephritis. The membranous lesion followed therapy with intravenous immune globulin, and the possibility that this intervention caused the renal disease must be considered. It appears that both of these lesions should be added to the list of possible complications of systemic-onset JRA.
全身型幼年类风湿性关节炎（JRA）是一种影响多个器官系统的复杂疾病。除淀粉样变性外，相关的肾脏病变并不常见。我们描述了一名患有全身型JRA的女孩，她首先出现膜性肾病，然后在3.5年后出现严重的新月体性肾小球肾炎。膜性病变发生在静脉注射免疫球蛋白治疗之后，必须考虑这种干预导致肾脏疾病的可能性。看来这两种病变都应列入全身型JRA可能的并发症清单中。
