Peterson R T, Schreiber S L
Howard Hughes Medical Institute, Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138, USA.
Curr Biol. 1998 Mar 26;8(7):R248-50. doi: 10.1016/s0960-9822(98)70152-6.
The identification of 3-phosphoinositide-dependent kinase 1 (PDK1) as one of the elusive 70 kDa S6 kinase kinases has filled a gap in the signaling pathway by which extracellular receptors regulate translation. Will it cause us to reconsider the relationships between previously identified members of the pathway?
将3-磷酸肌醇依赖性蛋白激酶1（PDK1）鉴定为难以捉摸的70 kDa S6激酶激酶之一，填补了细胞外受体调节翻译的信号通路中的一个空白。这会使我们重新考虑该信号通路中先前已确定的成员之间的关系吗？
