Vernooy C B, Jansen F W, Vandenbussche F P, Peters A A, van Roosmalen J
Afd. Verloskunde en Gynaecologie, Academisch Ziekenhuis, Leiden.
Ned Tijdschr Geneeskd. 1997 Sep 13;141(37):1761-4.
In four pregnant women, aged 28, 29, 30, and 35, malignancies were diagnosed: synoviosarcoma, gastric carcinoma, non-Hodgkin B cell lymphoma and undifferentiated adenocarcinoma in one of the labia vulvae, respectively. The first three women eventually died, the first before giving birth, the last woman was treated surgically and was alive without recurrence two years after treatment. Pregnancy can lead to diagnostic dilemma and delay as many symptoms of a malignancy are not recognised as such but are attributed to the pregnant state and because of reluctance to apply diagnostic tools which can be harmful to the foetus. It can also lead to therapeutic dilemma and delay because several therapies may also harm the foetus.
在4名年龄分别为28岁、29岁、30岁和35岁的孕妇中，分别诊断出恶性肿瘤：滑膜肉瘤、胃癌、非霍奇金B细胞淋巴瘤以及一侧大阴唇的未分化腺癌。前3名女性最终死亡，第一名在分娩前死亡，最后一名女性接受了手术治疗，治疗后两年仍存活且无复发。怀孕可能导致诊断困境和延误，因为许多恶性肿瘤的症状未被视为恶性肿瘤症状，而是归因于怀孕状态，并且由于不愿使用可能对胎儿有害的诊断工具。怀孕还可能导致治疗困境和延误，因为几种治疗方法也可能伤害胎儿。
