Espinet B, Solé F, Woessner S, Florensa L, Besses C, Sans-Sabrafen J
Laboratori de Citologia Hematològica, Hospital Central l'Aliança, Barcelona, Spain.
Cancer Genet Cytogenet. 1998 Apr 15;102(2):131-4. doi: 10.1016/s0165-4608(97)00315-4.
Tetraploid or near-tetraploid karyotype has been described rarely in hematologic neoplasms. Herein we report two new cases of adult acute myeloblastic leukemia, M0 and M1 FAB subtypes that showed near-tetraploid clones that were studied with conventional cytogenetics and in situ hybridization (ISH). We compare our new cases with those previously reported.
四倍体或近四倍体核型在血液系统肿瘤中鲜有报道。在此，我们报告两例新的成人急性髓系白血病病例，FAB亚型为M0和M1，其显示出近四倍体克隆，并通过传统细胞遗传学和原位杂交（ISH）进行了研究。我们将我们的新病例与先前报道的病例进行了比较。
