Lasek R J, Chren M M
Dermatology Service, Cleveland Veterans Affairs Medical Center, OH, USA.
Arch Dermatol. 1998 Apr;134(4):454-8. doi: 10.1001/archderm.134.4.454.
To determine the effects of acne vulgaris on the quality of life of adult dermatology patients.
Cross-sectional and longitudinal questionnaire study.
Sixty patients with acne vulgaris attending appointments with their dermatologists.
Findings using Skindex, a validated 29-item instrument to measure the effects of skin disease on patients' quality of life. Results are reported as 3 scale scores (functioning, emotions, and symptoms) and a composite score (average scale score). In addition, dermatologists rated the clinical severity of patients' skin disease, and patients responded to a global question about how they are bothered by acne. Higher Skindex scores indicate greater effects on quality of life.
Patients with acne experienced functioning and emotional effects from their skin disease comparable with those of patients with psoriasis, but experienced fewer symptoms (for patients with acne and psoriasis, respectively, Skindex functioning scores of 14.9 and 22.8 [P=.08]; emotion scores, 39.2 and 38.9 [P=.95]; and symptoms scores, 29.5 and 42.1 [P<.05]). Skindex scores were higher in older patients than in younger patients, and patients aged 40 years or older were less likely to report improvement in their acne after 3 months (43% vs 85%; P<.05). Among patients reporting no improvement in their acne, older patients reported greater effects of their acne on their quality of life. Furthermore, in multivariate analyses, older adults reported more effects of acne on their quality of life than younger adults, even after controlling for sex and acne severity as judged by the dermatologist.
Acne vulgaris significantly affects patients' quality of life. Regardless of the severity of acne, older adults were more affected by their acne.
确定寻常痤疮对成年皮肤科患者生活质量的影响。
横断面和纵向问卷调查研究。
60名前往皮肤科医生处就诊的寻常痤疮患者。
使用Skindex（一种经验证的29项工具，用于测量皮肤病对患者生活质量的影响）进行评估。结果以3个量表分数（功能、情绪和症状）和一个综合分数（平均量表分数）报告。此外，皮肤科医生对患者皮肤病的临床严重程度进行评分，患者回答一个关于痤疮对其困扰程度的总体问题。Skindex分数越高表明对生活质量的影响越大。
痤疮患者因皮肤病所经历的功能和情绪影响与银屑病患者相当，但症状较少（痤疮患者和银屑病患者的Skindex功能分数分别为14.9和22.8 [P = 0.08]；情绪分数分别为39.2和38.9 [P = 0.95]；症状分数分别为29.5和42.1 [P < 0.05]）。老年患者的Skindex分数高于年轻患者，40岁及以上的患者在3个月后痤疮改善的可能性较小（43% 对85%；P < 0.05）。在报告痤疮无改善的患者中，老年患者报告痤疮对其生活质量的影响更大。此外，在多变量分析中，即使在控制了性别和皮肤科医生判断的痤疮严重程度后，老年人报告痤疮对其生活质量的影响比年轻人更大。
寻常痤疮显著影响患者的生活质量。无论痤疮的严重程度如何，老年人受痤疮影响更大。
