Argento A, DiBenedetto R J
Department of Internal Medicine Education, Memorial Medical Center, Savannah, GA 31403, USA.
Chest. 1998 Apr;113(4):1136-8. doi: 10.1378/chest.113.4.1136.
The antiphospholipid antibody syndrome (APS) is typically characterized by recurrent arterial and/or venous thromboses, miscarriages, and thrombocytopenia. There have been five reported cases of ARDS associated with primary APS. Adrenal insufficiency has also been reported as a rare complication of APS. We report a case of both ARDS and adrenal insufficiency associated with primary APS. Chest radiographs and pulmonary angiography studies revealed findings consistent with ARDS. CT scans confirmed the presence of bilateral adrenal hemorrhagic infarction. Patients with APS are at an increased risk of widespread vascular thrombosis due to the presence of circulating antiphospholipid antibodies. This case emphasizes the importance of recognizing APS and its potential for multiple organ system involvement.
抗磷脂抗体综合征（APS）的典型特征为反复发生动脉和/或静脉血栓形成、流产及血小板减少。已有5例原发性APS相关急性呼吸窘迫综合征（ARDS）的报道。肾上腺功能不全也被报道为APS的一种罕见并发症。我们报告1例原发性APS相关的ARDS和肾上腺功能不全病例。胸部X线片和肺血管造影检查结果符合ARDS表现。CT扫描证实双侧肾上腺出血性梗死。由于循环中存在抗磷脂抗体，APS患者发生广泛血管血栓形成的风险增加。该病例强调了认识APS及其累及多器官系统可能性的重要性。
