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关于豚鼠胸段脊髓的营养网络。

On the vegetative network of guinea pig thoracic spinal cord.

作者信息

Galabov P, Davidoff M

出版信息

Histochemistry. 1976 Jun 28;47(3):247-55. doi: 10.1007/BF00489966.

DOI:10.1007/BF00489966
PMID:955977
Abstract

A dense AChE-positive network was visualized by light microscopy in the thoracic spinal cord of grown-up guinea pigs of both sexes (bodyweight 250-300 g). This network connects in a horizontal and vertical direction the preganglionic sympathetic nuclei (n. intermediolateralis pars principalis (ILp), n. intermediolateralis pars funicularis (ILf), n intercalatus spinals (IC), n. intercalatus pars paraependymalis (ICpe), (Petras and Cummings, 1972) all along the thoracic spinal cord. In addition to AChE activity, the bundles of fibers of this network also show a strong formaldehyde-induced NA fluorescence. Electron microscopy demonstrated granular vesicles in the cytoplasm of ILp cells. The surface of the ILp and IC neurons is almost entirely covered with synaptic bottons which have clear and granulated synaptic vesicles. The bundles of fibers consists of parallel myelin-free axones and dendrites. On their cource the axones form varicosities. In the varicosities and in the synaptic enlargements there are also clear and granulated (40-100 nm) vesicles. The probable origin of the vegetative network fibers of guinea pig thoracic spinal cord is discussed.

摘要

在成年雌雄豚鼠(体重250 - 300克)的胸段脊髓中,通过光学显微镜观察到一个密集的乙酰胆碱酯酶(AChE)阳性网络。该网络在水平和垂直方向上连接胸段脊髓全长的节前交感神经核(中间外侧核主部(ILp)、中间外侧核索部(ILf)、脊髓中间插入核(IC)、室管膜旁中间插入核(ICpe),(彼得拉斯和卡明斯,1972年)。除了AChE活性外,该网络的纤维束还显示出强烈的甲醛诱导的去甲肾上腺素(NA)荧光。电子显微镜显示ILp细胞的细胞质中有颗粒小泡。ILp和IC神经元的表面几乎完全被具有清亮和颗粒状突触小泡的突触小体覆盖。纤维束由平行的无髓轴突和树突组成。轴突在其行程中形成膨体。在膨体和突触膨大处也有清亮和颗粒状(40 - 100纳米)小泡。本文讨论了豚鼠胸段脊髓自主网络纤维的可能起源。

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