Strømme P, Valvatne K
Department of Paediatrics, Rikshospitalet, University of Oslo, Norway.
Acta Paediatr. 1998 Mar;87(3):291-6. doi: 10.1080/08035259850157345.
We wanted to determine the prevalence and subcategories of mental retardation (MR) defined as IQ < or = 70 in Akershus county, which rated by average yearly income, had the second highest socioeconomic status (SES) in Norway.
The study population consisted of 30 037 children born between 1980 and 1985. Cases were ascertained from multiple sources and psychometrically assessed, predominantly with the Wechsler tests, which were standardized in Norway in 1978. The cases were divided into four groups: profound (IQ < 20), severe (IQ 20-34), moderate (IQ 35-49), and mild (IQ 50-70) MR, according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV). The median age was 10.8 y. The frequency and degree of parental consanguinity were registered, and the average inbreeding coefficient was calculated.
Altogether, 185 had IQ < or = 70, giving a prevalence of MR of 6.2/1000. Prevalences for profound, severe, moderate, and mild MR were 0.8, 0.4, 1.5 and 3.5/1000, respectively. In two, possibly three, cases the parents were second cousins, giving an average inbreeding coefficient of 20-30 x 10(-5).
The low prevalence of MR, particularly mild MR, could partly be explained by high SES, old standardization of IQ-test, and low inbreeding coefficient. The proportion of profound MR was considerably higher than estimated by DSM-IV.
我们想确定在挪威社会经济地位(SES)第二高(以平均年收入衡量)的阿克什胡斯郡,智商(IQ)≤70所定义的智力迟钝(MR)的患病率及其亚类。
研究人群包括1980年至1985年出生的30037名儿童。通过多种来源确定病例并进行心理测量评估,主要采用1978年在挪威标准化的韦氏测试。根据《精神疾病诊断与统计手册》第4版(DSM - IV),将病例分为四组:极重度(IQ < 20)、重度(IQ 20 - 34)、中度(IQ 35 - 49)和轻度(IQ 50 - 70)智力迟钝。中位年龄为10.8岁。记录父母近亲结婚的频率和程度,并计算平均近亲繁殖系数。
共有185人的IQ≤70,智力迟钝的患病率为6.2/1000。极重度、重度、中度和轻度智力迟钝的患病率分别为0.8、0.4、1.5和3.5/1000。在两例可能三例病例中,父母为二级表亲,平均近亲繁殖系数为20 - 30×10⁻⁵。
智力迟钝的低患病率,尤其是轻度智力迟钝,部分原因可能是社会经济地位高、智商测试的旧标准化以及近亲繁殖系数低。极重度智力迟钝的比例明显高于DSM - IV的估计。