Aoki H, Sakai H, Kohsaka M, Konomi T, Hosoda J
J Antibiot (Tokyo). 1976 May;29(5):492-500. doi: 10.7164/antibiotics.29.492.
Nocardicin A is a new monocyclic beta-lactam antibiotic obtained from the fermentation broth of a strain of actinomycetes. The producing organism, strain WS 1571, was identified as Nocardia uniformis subsp. tsuyamanensis ATCC 21806. The antibiotic, obtained as colorless crystals, exhibits moderate in vitro antibacterial activity against a broad-spectrum of Gram-negative bacteria including Proteus and Pseudomonas. It has low toxicity in laboratory animals.
诺卡菌素A是一种从一株放线菌的发酵液中获得的新型单环β-内酰胺抗生素。产生该抗生素的菌株WS 1571被鉴定为均匀诺卡氏菌津山亚种ATCC 21806。该抗生素为无色晶体，对包括变形杆菌和假单胞菌在内的多种革兰氏阴性菌具有中等程度的体外抗菌活性。它在实验动物中的毒性较低。
